Weight-loss peptide research & sourcing guide

Understand weight-loss peptides. Then source them with confidence.

Mechanism-level profiles and agonist-class comparisons for GLP-1, dual, and triple agonist research compounds, plus current pricing from Core Power Peptides, the USA-made, third-party-tested supplier we vet and recommend.

99%+ purity, HPLC & MS verified
FDA-registered, cGMP-compliant US labs
Independent third-party lab testing
Fast 2–5 day US shipping
Discreet packaging
Free shipping over $100
Editor’s pick

Tirzepatide is the compound most researchers start with

Tirzepatide is the dual-agonist reference compound in this class, the one most newer multi-receptor agonists are measured against. The supplier we recommend is Core Power Peptides, and this is the vial we point researchers to first.

  • ≥99% purity, HPLC + MS/MS verified per batch
  • Dual GIP/GLP-1 receptor agonism, the reference compound for this research class
  • Third-party ISO-certified lab testing, COA available per lot
  • Ships from FDA-registered, cGMP-compliant US labs in 2–5 days

Disclosure: links marked “Shop” or “Check price” go to Core Power Peptides, our research-peptide supplier partner. We may earn a commission when you purchase through these links, at no added cost to you. This never changes which compounds we cover or how we describe them.

$320$416

50 mg vial · $6.40/mg · lyophilized powder
Struck-through price is the supplier’s own pre-sale listing. Checked Sep 29, 2026.

Category
GIP / GLP-1 Dual Agonist
Sequence length
39 amino acids
Research status
Approved analog exists
Best for
The dual-agonist most researchers reach for first
Check current price

How sourcing works

Research the compound

Review the mechanism, agonist class, and current research status for the peptide you are interested in.

Compare pathway and price

Weigh receptor pathway against current pricing across the GLP-1, dual, and triple agonist compounds we track.

Source from a vetted supplier

Buy directly from Core Power Peptides: USA-made, third-party tested, with a COA available for every batch.

Weight-loss peptide compounds

14 compounds studied across GLP-1, dual, and triple agonist pathways, plus growth-hormone and NNMT-adjacent research chemicals. Compounds currently in stock link straight to pricing.

GLP-1 compound pricing, compared

Current Core Power Peptides pricing for every incretin-pathway compound we track, so you can weigh mechanism against cost before choosing one to research.

CompoundPathwayBest forVialPrice$/mg
TirzepatideEditor's pick
GIP / GLP-1 Dual AgonistThe dual-agonist most researchers reach for first50 mg$320$416$6.40/mgShop
Semaglutide
GLP-1 Receptor AgonistSingle-pathway GLP-1 research; the reference comparator for newer agonists10 mg$75$7.50/mgShop
Cagrilintide
Long-Acting Amylin AnalogAmylin-pathway research, commonly paired with semaglutide10 mg$220$286$22.00/mgShop
Mazdutide
GLP-1 / Glucagon Dual AgonistGlucagon-pathway research as an alternative to GIP-based dual agonists10 mg$80$104$8.00/mgShop
Retatrutide
GIP / GLP-1 / Glucagon Triple AgonistThree-receptor (GIP, GLP-1, glucagon) mechanism research—Not stocked—Unavailable
Tesofensine
Triple Monoamine Reuptake InhibitorNon-incretin appetite-pathway research80 mg$109$1.36/mgShop
Liraglutide
GLP-1 Receptor AgonistA baseline GLP-1 comparator for newer incretin compounds—Not stocked—Unavailable
Orforglipron
Oral Non-Peptide GLP-1 AgonistOral, non-peptide GLP-1 pharmacology comparisons—Not stocked—Unavailable
Survodutide
GLP-1 / Glucagon Dual AgonistComparing GLP-1/glucagon dual agonism with three-receptor compounds—Not stocked—Unavailable

Prices checked Sep 29, 2026. $/mg is the listed price divided by vial size, so compounds are comparable per milligram. Struck-through figures are the supplier’s own pre-sale listings.

Disclosure: links marked “Shop” or “Check price” go to Core Power Peptides, our research-peptide supplier partner. We may earn a commission when you purchase through these links, at no added cost to you. This never changes which compounds we cover or how we describe them.

One receptor, two, or three: how the agonist classes differ

Each additional receptor pathway changes what researchers are studying, not just how strong the effect is.

Retatrutide

Triple agonist

Adds glucagon-receptor activation on top of GIP and GLP-1 signaling. The most mechanistically aggressive compound in this class, currently in late-stage trials.

3 of 3 receptor pathways

Semaglutide

GLP-1 only

Single-pathway incretin agonism. The reference point this entire research field is compared against.

Tirzepatide

GIP / GLP-1 dual

Combines two incretin pathways in one molecule, associated with larger mean reductions than GLP-1 alone.

What proper sourcing looks like, and why we point researchers to Core Power Peptides

These are the checks we use to evaluate any supplier before recommending it. Core Power Peptides is the one we currently vouch for: FDA-registered, cGMP-compliant US labs, ≥99% purity on every batch, and independent ISO-certified lab verification.

Meets this

Certificate of analysis

Every batch should ship with a COA verifying purity and identity through HPLC or mass spectrometry, not a generic template.

Meets this

Independent third-party testing

In-house testing alone is not enough. Look for sourcing that is verified by a lab outside the manufacturer.

Meets this

Cold-chain handling

Lyophilized peptides tolerate brief room-temperature shipping, but need refrigerated or frozen storage for long-term stability.

Reconstitution basics

Bacteriostatic water, sterile technique, and gentle swirling rather than shaking, which can denature the peptide.

Meets this

Batch traceability

Lot numbers printed on the vial should trace back to a specific, dated certificate of analysis.

Latest research

All articles

Frequently asked questions

Research peptides sold for laboratory use sit in a regulatory gray area in most jurisdictions. Some compounds discussed here, including semaglutide and tirzepatide, also exist as FDA-approved prescription drugs sold only through pharmacies. Nothing on this site is intended for human use, self-administration, or as medical advice.

Disclosure: links marked “Shop” or “Check price” go to Core Power Peptides, our research-peptide supplier partner. We may earn a commission when you purchase through these links, at no added cost to you. This never changes which compounds we cover or how we describe them.

Ready to source your next compound?

Every compound on this site can be checked against current Core Power Peptides pricing and stock. Third-party tested, USA-made, and shipped in 2–5 days.

Shop Core Power Peptides

Disclosure: links marked “Shop” or “Check price” go to Core Power Peptides, our research-peptide supplier partner. We may earn a commission when you purchase through these links, at no added cost to you. This never changes which compounds we cover or how we describe them.